Obscure virus found in women with unexplained infertility

Obscure virus found in women with unexplained infertility

The little-known member of the human herpesvirus family called HHV-6A infects the lining of the uterus in 43 percent of women with unexplained infertility but cannot be found in that of fertile women, researchers have discovered. The study also reported that the infection is exacerbated by hormone estradiol. Estradiol fluctuates with the menstrual cycle. High levels may trigger an active infection localized in the uterus.

A new study has found that the little-known member of the human herpesvirus family called HHV-6A infects the lining of the uterus in 43% of women with unexplained infertility but cannot be found in uterine lining of fertile women. The study was conducted by investigators at the University of Ferrara, Italy.

Presence of HHV-6A in Endometrial Epithelial Cells from Women with Primary Unexplained Infertility. PLOS ONE, 2016; 11 (7): e0158304 DOI: 10.1371/journal.pone.0158304